Oklahoma's healthcare system includes major regional networks, specialized research centers, and rural community hospitals.
* **OU Health** (Oklahoma City): The state's flagship academic health system, featuring the only Level 1 Trauma Center in Oklahoma and the Stephenson Cancer Center. * **Integris Health**: The state's largest not-for-profit health system, with hospitals and clinics across Oklahoma. * **Saint Francis Health System**: Based in Tulsa, anchored by Saint Francis Hospital, a major regional anchor and Level 2 Trauma Center. * **Mercy**: Operates major hospitals in Oklahoma City, Ada, and throughout regional communities. * **Tribal Health Systems**: The Cherokee, Choctaw, and Chickasaw Nations, among others, operate extensive, highly-rated medical centers and clinics serving both tribal citizens and the broader community.