Lusby experiences a humid subtropical climate (Köppen climate classification *Cfa*), featuring four distinct seasons.
* **Summers** are hot and highly humid, with average high temperatures in the mid-to-upper 80s°F (29–32°C). Thunderstorms are common in the late afternoons. * **Winters** are generally cool to mild, with average highs in the 40s°F (4–9°C). Snowfall occurs but is typically light and ephemeral, averaging about 10-15 inches annually. * **Spring and Fall** are widely considered the best times to visit, offering comfortable temperatures, lower humidity, and vibrant foliage or blooming flora.
Precipitation is relatively evenly distributed throughout the year, averaging around 45 inches annually. Because of its coastal location, Lusby is occasionally impacted by the remnants of Atlantic hurricanes or strong winter nor'easters, which can cause localized coastal flooding and wind damage.

